Patients with immunodeficiency

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1.Measles prognosisMeasles is usually mild. Small, malnourished children and  are particularly at risk of a severe course of the disease and a high risk of complications.Death from measles occurs mainly as a result of complications. In the group of malnourished people and with no access to appropriate medical care, the mortality rate reaches 10%.Measles complicationsComplications in the course of measles occur in 30%. cases.

Children especially often suffer from complications:malnourished,with rickets,with heart defects,with other chronic diseases,small children up to 2 years of age,adults with immunodeficiency.The most common complications of measles include:Otitis media, which occurs in 7-9 percent. measles cases.Pneumonia, which occurs in 1-6 percent. cases. Usually, it is severe, often with symptoms of respiratory and circulatory failure, and has a high mortality.

Laryngitis and tracheitis.Inflammation of the bronchi and bronchioles.Encephalitis occurring in 0.1% of cases. It runs with coma and convulsions and is burdened with 15 percent. mortality and 25 percent. the risk of permanent neurological complications such as intellectual retardation, paralysis and paresis, epilepsy and deafness.Inflammation of the cornea, which can progress to corneal ulceration and blindness.Death occurs in 0.1-1 cases per 1,000 cases (in infants in developing countries, mortality is as high as 20-30%).

Subacute sclerosing panencephalitis (SSPE) is rare (1-4 / 100,000 cases), but in children under two years of age it is even 1/8000. It is a late complication that occurs as a result of latent infection2, several years after the onset of measles (seven years on average). The disease is progressive – from impaired mental and motor skills, speech disorders, behavioral changes, to complete dementia, paresis and brain wasting, which inevitably leads to death.

 

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