Major scientific achievements over the last decade include: -Original description of the vascular pathogenesis of Crohn’s disease -Original description of thrombotic mechanisms in inflammatory bowel disease -Discovery of measles virus in inflammatory bowel disease -Original description of the atypical patterns of exposure to the measles virus that are a risk for inflammatory bowel disease -Setting up UK’s National Register of Pediatric Inflammatory Bowel Disease -Original description of the vascular pathogenesis of enteropathy induced by nonsteroidal anti- inflammatory drugs -Original description of intestinal pathology in children with developmental disorder autistic enterocolitis -Development of novel in cell gene amplification technologies for virus detection in diseased tissues -Discovery of measles virus in intestinal tissues from children with autistic enterocolitis